The side effects of corticosteroids on lupus treatment

April 14th, 2010

the_side_effects_of_corticosteroids_as_lupus_drugThe benefits of corticosteroids in lupus treatment can be measured in terms of increased life expectancy. In 1955, the survival rate at five years for lupus patients was only 50%. By 1995, the survival rate at 20 years had already reached 80%. In fact, many women stay healthy to keep their works for decades after diagnosis with lupus disease.

Even though corticosteroids have a benefit in lupus treatment, the risks of corticosteroids are serious enough to warrant very careful dosage adjustments and monitoring, as well as the addition of steroid-sparing drugs. The doctor describes both long term and short term side effects. The short term effects, which can generally be reversed by decreasing the dose, are:

  1. Mood changes. Some feel energetic and euphoric, while others feel depressed or irritable. Different people react differently.
  2. Facial hair. Some patients notice coarser or more plentiful facial hair.
  3. High blood sugar. Diabetics may require a change in their therapy, and patients at risk for diabetes need careful monitoring.
  4. Acne. This may start or get worse with corticosteroids.
  5. Increased risk of infections. Since inflammation is our first line of defense against infections of all types, all anti-inflammatory medications increase the risk. Corticosteroids are powerful enough to be of great concern.
  6. Water retention or Swelling. These medications influence the body’s transport of salts. Patients may notice swelling at some part of the body especially of the ankles.

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3 Responses to “The side effects of corticosteroids on lupus treatment”

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